Dr. Gondru Ramesh is a Scientist-C in the Food Chemistry Division at ICMR–National Institute of Nutrition (NIN), where he has been serving since January 2023. His research focuses on the comprehensive nutritional, antinutritional, and phytochemical evaluation of exotic and underutilized non-timber food products (NTFPs), including wild fruits and underutilized green leafy vegetables (UGLVs). He is particularly interested in exploring the nutraceutical potential of wild edible plants and isolating bioactive natural products from them.

He earned his Ph.D. in Chemistry from the National Institute of Technology (NIT) Warangal in 2018 under the supervision of Prof. B. Rajitha (Late), with a thesis titled Design, Synthesis, and Biological Evaluation of New Heterocyclic Hybrids. His doctoral research involved the synthesis of novel heterocyclic hybrids for medicinal chemistry applications and the development of green synthetic protocols for small bioactive molecules.

Before joining NIN, he worked as Scientist-B at ICMR–National Institute for Research in Environmental Health (NIREH), where he specialized in the synthesis of Metal–Organic Frameworks (MOFs) for the adsorptive removal of aromatic volatile organic compounds (VOCs). He also served as a part-time Assistant Professor in the Department of Chemistry at Kakatiya University.

Dr. Ramesh is recognized as a Ph.D. guide in Chemistry by Osmania University and has also been recognized as an Assistant Professor and Ph.D. guide by the Academy of Scientific and Innovative Research (AcSIR). He is an active member of professional bodies including the American Chemical Society (ACS), the Nutritional Society of India (NSI), and the Indian Council of Chemists (ICC).

1. Chandrakanth, M.; Kumari, J.; Bisla, S.; Pasupuleti, M.; Gondru, R.; Arockiaraj, J.; Sriram, D.; Banothu, J. Design, Synthesis, and Identification of Benzimidazole–Acrylonitriles, Coumarin–Benzimidazole/Benzothiazole Hybrids as Potential Antitubercular Agents. J. Mol. Struct. 2026, 1367, 146149. https://doi.org/10.1016/j.molstruc.2026.146149.
2. Thomas, N. M.; Kallingal, A.; Maciejewska, N.; Chandrakanth, M.; Salunke, D. B.; Petrovsky, N.; Kundil, V. T.; Abhithaj, J.; Alharbi, M.; Narajczyk, M.; Gondru, R.;Pasangha, C. H.; Banothu, J. Discovery of 1,2-Dihydro-4-Hydroxy-2-Oxoquinoline-3- Carboxamide Derivatives as Potent Anticancer Agents: Structure-Based Design, Synthesis, Mechanistic Insights, Target Identification, and Molecular Docking Studies. Bioorg. Chem. 2026, 175, 109783. https://doi.org/10.1016/j.bioorg.2026.109783.
3. Chandrakanth, M.; Kumari, J.; Pakhira, P.; Sriram, D.; Busi, S.; Ranganathan, S.; Kumari, C.; Bisla, S.; Pasupuleti, M.; Gondru, R.; Arockiaraj, J.; Banothu, J. 2- Aminothiophene and 2-Aminothiazole Scaffolds as Potent Antimicrobial Agents: Design, Synthesis, Biological Evaluation, and Computational Insights. Bioorg. Chem. 2026, 170, 109511. https://doi.org/10.1016/j.bioorg.2026.109511.
4. Jadhaw, B.; Kumar, C. B.; Vasapalli, K.; Pranathi, K. S.; Ramesh, G.; Misra, S.; Kaki, S. S. Novel Isoniazid–Based 1,3,4‐Oxadiazole–Fatty Acid Hybrids: Synthesis, In Vitro Biological Activity and In Silico ADME/Tox Predictions. Chem. Biodivers. 2026, 23 (1). https://doi.org/10.1002/cbdv.202502042.
5. Chandrakanth, M.; Mishra, S.; Gayathri, K.; Katreddy, R. R.; Ranganathan, S.; C G, A.; Gondru, R.; Rajasekaran, S.; Banothu, J. Fused Thiophene – Benzimidazole Conjugates Targeting EGFR: Design, Synthesis, Anticancer Evaluation and Their Mechanistic Insights. Eur. J. Med. Chem. 2026, 303, 118435. https://doi.org/10.1016/j.ejmech.2025.118435.
6. Arya, C. G.; Thomas, N. M.; Chandrakanth, M.; Kallingal, A.; Amrutha, P. G.; Sivapriya, M. S.; Gondru, R.; Banothu, J. Coumarin–Benzimidazole Hybrids: Design, Synthesis and Identification of Potential Anticancer Agents. Bioorg. Med. Chem. Lett. 2026, 131, 130444. https://doi.org/10.1016/j.bmcl.2025.130444.
7. Fabitha, K.; Chandrakanth, M.; Kallingal, A.; Maciejewska, N.; Telukuntla, P.; Gondru, R.; Kumavath, R.; Demina, T. D.; Alharbi, M.; Banothu, J. Identification of Pyrazole- Acrylonitrile Derivatives as Potential Anticancer Agents and Mechanistic Insights. Bioorg. Med. Chem. 2025, 130, 118352. https://doi.org/10.1016/j.bmc.2025.118352.
8. C. G., A.; Kumari, J.; Busi, S.; Salim, S. A.; Chandrakanth, M.; Sriram, D.; Gondru, R.; Banothu, J. Design, Synthesis and Antimycobacterial Evaluation of Benzimidazole- Thiazolylhydrazone Derivatives: In Silico Molecular Docking Studies, DFT Analysis and ADMET Predictions. Synth. Commun. 2025, 55 (10), 758–773. https://doi.org/10.1080/00397911.2025.2498535.
9. Palabindela, R.; Bodapati, R.; Myadaraveni, P.; Ramesh, G.; Kasula, M. Synthesis, Docking Studies, in Silico ADMET Predictions, DFT Calculations, and Photophysical Properties of Thiazole-Anthracene Hybrids as Potent EGFR Inhibitors. J. Mol. Struct. 2024, 1317, 139067. https://doi.org/10.1016/j.molstruc.2024.139067.
10. Arya, C. G.; Kishore, R.; Gupta, P.; Gondru, R.; Arockiaraj, J.; Pasupuleti, M.; Chandrakanth, M.; Punya, V. P.; Banothu, J. Identification of Coumarin – Benzimidazole Hybrids as Potential Antibacterial Agents: Synthesis, in Vitro and in Vivo Biological Assessment, and ADMET Prediction. Bioorg. Med. Chem. Lett. 2024, 110, 129881. https://doi.org/10.1016/j.bmcl.2024.129881.
11. Telukuntla, P.; Chandrakanth, M.; Amrutha, P. G.; Thomas, N. M.; Gondru, R.; Valluru, K. R.; Banothu, J. 1,2,3-Triazole – [1,2,4]Triazolo[3,4-b][1,3,4]Thiadiazine Hybrids: A Switch for Improvement of Antibreast Cancer Activity Targeting Epidermal Growth Factor Receptor. Tetrahedron Lett. 2024, 146, 155180. https://doi.org/10.1016/j.tetlet.2024.155180.
12. Muripiti, V.; Velidandia, A.; Sharma, Y. P.; Gondru, R.; Arya, C. G.; Banothu, J. Targeted Gene Delivery through Receptors with Lipid Nanoparticles. J. Drug Deliv. Sci. Technol. 2024, 93, 105457. https://doi.org/10.1016/j.jddst.2024.105457.
13. Chirra, S.; Gondru, R.; Manne, M.; Azam, M.; Al-Resayes, S. I.; Manchal, R.; Narsimha, S. Synthesis of [1,2,4]Triazolo[3,4-b][1,3,4]Thiadiazine-1,2,3-Triazoles as Potent EGFR Targeting Anti-Breast Cancer Agents. J. Mol. Struct. 2024, 1306, 137803. https://doi.org/10.1016/j.molstruc.2024.137803.
14. Muripiti, V.; Ravula, V.; Batthula, S.; Banothu, J.; Gondru, R. Phenylboronic Acid- Derived Nanovectors for Gene/Drug Delivery by Targeting Cell Surface Glycans. RSC Pharmaceutics 2024, 1 (3), 403–411. https://doi.org/10.1039/D4PM00005F.
15. Fabitha, K.; Kallingal, A.; Maciejewska, N.; Arya, C. G.; Chandrakanth, M.; Thomas, N. M.; Li, Y.; Gondru, R.; Munikumar, M.; Banothu, J. Novel Fused Pyran Derivatives Induce Apoptosis and Target Cell Cycle Progression in Anticancer Efficacy against Multiple Cell Lines. New Journal of Chemistry 2024, 48 (18), 8038–8054. https://doi.org/10.1039/D4NJ00824C.
16. G, A. C.; Gondru, R.; Li, Y.; Banothu, J. Coumarin–Benzimidazole Hybrids: A Review of Developments in Medicinal Chemistry. Eur. J. Med. Chem. 2022, 227, 113921. https://doi.org/10.1016/j.ejmech.2021.113921.
17. Arya, C. G.; Chandrakanth, M.; Fabitha, K.; Thomas, N. M.; Pramod, R. N.; Gondru, R.; Banothu, J. Coumarin – Benzimidazole Hybrids: A Review on Diverse Synthetic Strategies. Results Chem. 2022, 4, 100631. https://doi.org/10.1016/j.rechem.2022.100631.
18. Ramya Sucharitha, E.; Krishna, T. M.; Manchal, R.; Ramesh, G.; Narsimha, S. Fused Benzo[1,3]Thiazine-1,2,3-Triazole Hybrids: Microwave-Assisted One-Pot Synthesis, in Vitro Antibacterial, Antibiofilm, and in Silico ADME Studies. Bioorg. Med. Chem. Lett. 2021, 47, 128201. https://doi.org/10.1016/j.bmcl.2021.128201.
19. Gondru, R.; Kanugala, S.; Raj, S.; Ganesh Kumar, C.; Pasupuleti, M.; Banothu, J.; Bavantula, R. 1,2,3-Triazole-Thiazole Hybrids: Synthesis, in Vitro Antimicrobial Activity and Antibiofilm Studies. Bioorg. Med. Chem. Lett. 2021, 33, 127746. https://doi.org/10.1016/j.bmcl.2020.127746.