Scientist 'F' &HOD Animal Facility
Coordinator Preclinical Toxicology and Convener of Laboratory Business Group


Email:   ssyhq@yahoo.com
Contact:  +91-40-27197201

Brief Profile

He graduated in 1985 and completed a post-graduate programme in veterinary pathology in 1987 from the College of Veterinary Sciences, Andhra Pradesh. He joined the National Centre for Laboratory Animal Sciences (NCLAS), ICMR-National Institute of Nutrition (NIN) in 1988 as a Research Officer and served the centre for 10 years in the capacity of a lab animal veterinarian and veterinary pathologist, handling health monitoring of the animals. In 1999, he moved to the Pathology Division of the ICMR-NIN and handled Lab Animal Pathology, Experimental Pathology and Toxicopathology. He was invited to work under the direct supervision of the Union Minister, Government of India, as an Expert consultant on deputation to the, “Committee for the Purpose of Control and Supervision of Experiments on Animals" (CPCSEA), headed by the Union Minister. He underwent the Certificate course on Laboratory Animal Science at the University of Utrecht, Utrecht, The Netherlands, in 2002. He worked for 3 years as an advisor and Expert Consultant to the CPCSEA headed by the Union Minister, Government of India, implementing animal welfare laws in India. He founded the "Laboratory Animal Scientist’s Association of India" in 2004. He is also the founding Father of the Indian College of Veterinary Pathologists, Indian Veterinary Research Institute, Izatnagar. He passed the Board Certification Examination of the Indian College of Veterinary Pathologists and was conferred the Diploma of the ICVP in 2008.
He served as a member of the Committee for International Guidelines on "Threat of Extremism to Medical Research" of the Federation of American Societies for Experimental Biology (FASEB), June 11–12, 2012, Bethesda, Maryland, USA and he is also a member of the Strategic Planning Committee of the American Associations for Accreditation of Laboratory Animal Care International (AAALAC), USA. He presented a poster on "Innovative approaches in non-clinical safety evaluation of oral recombinant anti-Human Papilloma Virus vaccine (Hpv 16 and 18) in mice and rats" during the 17th World Congress of Basic and Clinical Pharmacology (WCP2014) in 2014 at the CTICC in Cape Town, South Africa.
He has published 44 papers in scientific peer reviewed journals. He is the architect of the FELASA ‘C’ accredited course in Laboratory Animal Science being offered at the Tamil Nadu Veterinary and Animal Sciences University, Chennai. He was a visiting scientist at the National Jewish Hospitals, Denver and the Oklahoma Medical Research Foundation, Oklahoma, USA. He served as Assistant Director (Veterinary Pathologist) in the Pathology Division, National Institute of Nutrition (ICMR), Hyderabad for 15 years and is presently working as Scientist ‘F’ Senior Deputy Director, Head of Animal Facility, Coordinator of Preclinical Toxicology and Convener of Laboratory Business Group at the ICMR-NIN, Hyderabad.

Total publications : 44 Last 10 years: 25
  1. Mir, I. A.; Manjunathachar, H.; Naik, R. R.; Qadri, S.; Saleem, T. Rodent and Non-Rodent Animal Models for CardioVascular Diseases. Advancements in Cardiovascular Research and Therapeutics: Molecular and Nutraceutical Perspectives 2022, 52–78. https://doi.org/10.2174/9789815050837122010007.
  2. Mohammed, S.; Qadri, S. S. Y.; Mir, I. A.; Kondapalli, N. B.; Basak, S.; Rajkumar, H. Fructooligosaccharide Ameliorates High-Fat Induced Intrauterine Inflammation and Improves Lipid Profile in the Hamster Offspring. Journal of Nutritional Biochemistry 2022, 101, 108925. https://doi.org/10.1016/j.jnutbio.2021.108925.
  3. Korra Mangthya, Pradeep B. Patil1, R. Ananthan, K. Subash, T Longvah, SSYH Qadri; Evaluation of Superoxide Dismutase Levels in Rodent Visceral Organs and Tissues after Feeding a Diet Fortified with Chilli for Three Monthsepra. International Journal of Multidisciplinary Research (IJMR) 2455-3662. 2022, 3662 (Sjif), 201811. https://doi.org/10.36713/epra10898.
  4. Korra Mangthya, Pradeep B. Patil1, R. Ananthan, K. Subash, T Longvah, SSYH Qadri; Effect of 3 Months-Feeding of a Powder Diet Fortified with Chilli (Guntur, Bird’s Eye, And Naga King) on Superoxide Dismutase Levels in SD Rat. International Journal of Multidisciplinary Research (IJMR) 2455-3662. 2022, 3662 (Sjif), 2022:8.205. https://doi.org/10.36713/epra10858.
  5. Srinivasa Reddy, Y.; Narendra Babu, K.; Qadri, S. S. Y. H.; Surekha, M. V.; Dinesh Kumar, B. An Innovative Method of Nonclinical Efficacy and Toxicological Evaluation of Recombinant Salmonella Typhi Ty21a Expressing HPV16 and 18 L1 Proteins. MethodsX 2021, 8. https://doi.org/10.1016/j.mex.2021.101219.
  6. Srinivasa Reddy, Y.; Narendra Babu, K.; Uday Kumar, P.; Qadri S. S. Y. H.; Surekha, M. V.; Dinesh Kumar, B. Toxicological Data of Rats and Rabbits: Sub-Chronic Testing of Recombinant HPV Vaccine through Oral and Intranasal Routes. Data in Brief 2021, 36, 107100. https://doi.org/10.1016/j.dib.2021.107100.
  7. Singh, V.; Singh, A.; Qadri, S. S. Y. H.; Surekha, M. V.; Mahesh, J.; Rao, B.; Harishankar, N.; Kumar, B. D. Pharmacological Properties of DurvaSwaras (CynodonDactylon L. Pers.) in an Ovariectomised Rat Model Mimicking Chronic Menopausal Syndrome. Biomedicine and Pharmacotherapy 2021, 142, 111976. https://doi.org/10.1016/j.biopha.2021.111976.
  8. Srinivasa Reddy Y, Narendra Babu K, Uday Kumar P, Harishankar N, Qadri SSYH, Surekha MV, Hemalatha R, Dinesh Kumar B. Nonclinical safety evaluation of oral recombinant anti-human papilloma virus vaccine (RHPV 16 & 18): Regulatory toxicology studies in mice, rats and rabbits - An innovative approach. Vaccine. 2021 Jan 29;39(5):853-863. doi: 10.1016/j.vaccine.2020.11.023.
  9. Khandare, A. L., Kalakumar, B., Validandi, V., Qadri, S. S. Y. H., Harishankar, N., Singh, S. S., & Kodali, V. (2020). Neurolathyrism in goat (Capra hircus) kid: Model development. Research in Veterinary Science, 132, 49-53. https://doi.org/10.1016/j.rvsc.2020.05.019.
  10. Nadella, V., Ranjan, R., Senthilkumaran, B., Qadri, S.S.Y.H., Pothani, S., Singh, A.K., et al. (2019) Retraction: Podophyllotoxin and Rutin Modulate M1 (iNOS+) Macrophages and Mitigate Lethal Radiation (LR) Induced Inflammatory Responses in Mice. Immunol. 10:106. Frontiers Editorial Office. (2022). doi: 10.3389/fimmu.2019.00106
  11. Naik, R. R.; Nemani, H.; Pothani, S.; Pothana, S.; Satyavani, M.; Qadri, S. S.; Srinivas, M.; Parim, B. Obesity-Alleviating Capabilities of Acalypha Indica, PergulariAdemia and TinosporaCardifolia Leaves Methanolic Extracts in WNIN/GR-Ob Rats. Journal of Nutrition and Intermediary Metabolism 2019, 16 (February), 100090. https://doi.org/10.1016/j.jnim.2019.02.001.
  12. Mohammed S, Hemalatha R, Qadri SSYH, Annapurna VV. Semi-synthetic diet versus diet using natural ingredients-Comparative study in female Golden Syrian hamsters. J AnimPhysiolAnimNutr (Berl). 2019 Mar;103(2):687-694. doi: 10.1111/jpn.13035. Epub 2019 Jan 18.
  13. Qadri, S. S., & Ramachandra, S. G., Laws, regulations, and guidelines governing research animal Care and use in India. In Laboratory animals, 2018, (pp. 237-261). Academic Press. https://doi.org/10.1016/B978-0-12-849880-4.00008-8.
  14. Khan, N., Touheed Ahmed, S., Waheed, M., S. Y. H. Qadri, Ali, Y., Rasheed, N. M., & Parveen, N. (2017). In vitro evaluation of antioxidant potential and in vivo studies for preclinical toxicity with hepatoprotective activity of Safoof-e-akseer-e-jigar.
  15. Noolu, B., Gogulothu, R., Bhat, M., SYH Qadri, S., Sudhakar Reddy, V., Bhanuprakash Reddy, G., & Ismail, A. (2016). In vivo inhibition of proteasome activity and tumour growth by Murrayakoenigii leaf extract in breast cancer xenografts and by its active flavonoids in breast cancer cells. Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents), 16(12), 1605-1614.
  16. Tiwari, P., Sahay, S., Pandey, M., Qadri, S. S.H., & Gupta, K. P. (2016). Preventive effects of butyric acid, nicotinamide, calcium glucarate alone or in combination during the 7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis via modulation of K-Ras-PI3K-AKTpathway and associated micro RNAs. Biochimie, 121, 112-122. https://doi.org/10.1016/j.biochi.2015.11.027.
  17. Kumar, B. K., Reddy, A. G., Krishna, A. V., Quadri S. S. Y. H., & Kumar, P. S. (2016). Developmental neurotoxicity of monocrotophos and lead is linked to thyroid disruption. Veterinary World, 9(2), 133. doi: 10.14202/vetworld.2016.133-141
  18. Tiwari, P., Sahay, S., Pandey, M., Qadri, S. S.Y.H., & Gupta, K. P. (2015). Combinatorial chemopreventive effect of butyric acid, nicotinamide and calcium glucarate against the 7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis attained by enhancing the induction of intrinsic apoptotic events. Chemico-biological interactions, 226, 1-11. https://doi.org/10.1016/j.cbi.2014.11.018.
  19. Bhaskarachary, K., Ramulu, P., Udayasekhararao, P., Bapurao, S., Krishnaswamy, K., Syed, Q., ... &Sesikeran, B. (2014). Chemical Composition, Nutritional and Toxicological Evaluation of Peanut (Arachis hypogea) Grown in Fly Ash Amended Soils. The Indian Journal of Nutrition and Dietetics, 11-22.
  20. Bhat, M., Noolu, B., Qadri, S. S., & Ismail, A. (2014). Vitamin D deficiency decreases adiposity in rats and causes altered expression of uncoupling proteins and steroid receptor coactivator3. The Journal of steroid biochemistry and molecular biology, 144, 304-312. https://doi.org/10.1016/j.jsbmb.2014.08.005.
  21. Bhat, M., Kalam, R., Qadri, S. S., Madabushi, S., & Ismail, A. (2013). Vitamin D deficiency-induced muscle wasting occurs through the ubiquitin proteasome pathway and is partially corrected by calcium in male rats. Endocrinology, 154(11), 4018-4029.  https://doi.org/10.1210/en.2013-1369.
  22. Shirfule, A. L., Racharla, V., Qadri, S. S. Y. H., &Khandare, A. L. (2013). Exploring antiurolithic effects of gokshuradi polyherbal ayurvedic formulation in ethylene-glycol-induced urolithic rats. Evidence-Based Complementary and Alternative Medicine, 2013. https://doi.org/10.1155/2013/763720.
  23. Kumar, B. K., Qadri, S. S. Y. H., Kumar, B. V., & Reddy, A. G. (2013). Use of Propofol and Xylazine Combination for Use in Small Animal Densitometry. Indian Vet. J, 90(6), 106-107.
  24. Putcha, U., Ayyalasomayajula, V., Mullapudi, S., Qadri, S. S. Y. H., Krishnakumar, S., Subramanyam, K., &Boindala, S. (2013, January). Role of type of dietary fat in the etio-pathogenesis of carcinogen-induced breast neoplasm in female fischer rats. in annals of nutrition and metabolism (Vol. 63, pp. 1329-1329). ALLSCHWILERSTRASSE 10, CH-4009 Basel, Switzerland: Karger.
  25. Kalpana, G. V., Chandrashekar, K., Kumar, S. N., &Qadri, S. (2013). Adoption of Innovative Technologies for Labour Saving in Silkworm Seed Crop Rearing by the Progressive Farmer–A Case Study.
Books & book chapters/International Guidelines:
  1. Irfan Ahmad Mir, HV Manjunathachar, R Ravindar Naik, SSYH Qadri and Taniya Saleem. “Rodent and Non-Rodent Animal Models for Cardio-Vascular Diseases Advancements in Cardiovascular Research and Therapeutics”, 2022, 1-27.
  2. Panneer D, Syed SYH Qadri, ThirumurthyMadhavan, Gnanasambandan R, “A Hand-Book on Laboratory Animal Science, Experimentation and Welfare”, published 2021 pp 1-55, ICMR-Vector Control Research Centre, Puducherry.
  3. Pradeep B. Patil1, Majunathachar H. V, Irfan Ahmad Mir, SSYH Qadri. “Experimental Animal Facility Management in India: Problems and prospects”, ICMR-National Institute of Nutrition, Tarnaka, Hyderabad-500007, ICMR- National Animal Resource Facility for Biomedical Research, Shamirpet, Hyderabad-500076.
  4. Takhar, M., Alshalalfa, M., Gupta, A., SSYH Qadri& Prasad, S. (2018). Sientific program of 36th World Congress of endourology Programm Book. J. Endourol, 32, P1-A573.
  5. Syed SYH Qadri, “International Historical Perspectives - Conference report of the Federation of American Societies for Experimental Biology (FASEB), The threat of Extremism to Medical Research: An International Summit”, June 11-12, 2012, Bethesda, Maryland, USA.
  6. Syed SYH Qadri and Christian E. Newcomer: Chapter: “Laws, Regulations, and Guidelines Shaping Research Animal Care and Use in India, Chapter 8, pp 219 – 242, Academic Press. 2014.
  7. Syed SYH Qadri and SG Ramachandra, Laboratory AnimalsRegulations and Recommendations for the Care and Use of Animals in Research2nd Edition - October 25, 2017, Laboratory Animals, Editor, Javier Guillén, Elsevier, Academic Press. 2018.
Awards and Honors
  1. Awarded the "Bhagwan Mahaveer Vishwa Sadhbhavana Puraskar-1999", for Environment and Animal Protection by the Mahaveer Sangh Andhra Pradesh.
  2. Telangana State Agricultural University, Rajendranagar, Hyderabad awarded Gold Medal for securing highest marks in Veterinary Pathology.
  3. Young Scientist Award for the work on Sendai virus by the Indian Association of Veterinary Pathologist in 1995.
Recognitions
  1. Special Invited Guest to the American College of Laboratory Animal Medicine (ACLAM) Annual Convention, April 2013 at Williamsburg, Virginia, USA.
  2. Visiting Scientist – National Jewish Hospitals, Denver, USA. 13th - 21st June 2012.
  3. Founder and served as Secretary General, Laboratory Animal Scientist’s Association of India, 2004.
  4. Executive Member of Indian College of Veterinary Pathologists, National Institute of Nutrition Scientists Association&Asian Federation of Laboratory Animal Sciences, Japan.
  5. Secretary, Large Animal Subcommittee, CPCSEA, Ministry of Environment & Forests, Government of India.
  6. Member, Subcommittee on Alternative to Animal Experiments, CPCSEA, Ministry of Environment & Forests, Government of India.
  7. Honorary Animal Welfare Officer of the Animal Welfare Board of India, Ministry of Environment & Forests, Government of India 1992 – 1998.
  8. Founder and Vice President, People for Animals, Hyderabad and Secunderabad - 1998
  9. Founder and Joint Secretary, Society for Prevention of Cruelty to Animals, Hyderabad and Secunderabad – 1994
  10. Member of Expert Group for preparation of Detailed Project Report (DPR) Document for establishing National Institutes for Research in Ayurveda, Department of Ayush, Ministry of Health & Family Welfare, Government of India.
  11. Joint Secretary of the Indian Association of Veterinary Pathologists.
  12. Executive Committee member of the Indian College of Veterinary Pathologists.
  13. Examination Committee member of the Indian College of Veterinary Pathologists.
  14. Member of the Board of Studies for Science (Zoology) in the Yogi Vemana University, Kadapa.
Professional memberships
  1. Registered member of the Veterinary Council of India.
  2. Registered member of the A.P. Veterinary Council.
  3. Member of Indian Veterinary Association.
  4. Founding Father and Chartered Member of the Indian College of Veterinary Pathologist, IVRI, Izatnagar.
  5. Indian Association of Veterinary Pathologists.
  6. Registered Life member of Society for Toxicologic Pathologists in India.
  7. Founder and Gen. Secretary – All India ‘Laboratory Animal Scientist’s Association’.