Dr. Ayesha IsmailScientist ‘E'
Dr. Ismail has a Master’s degree in Biochemistry from the University of Hyderabad and Ph.D in Biochemistry from Osmania University, Hyderabad. Before joining NIN in 2008, she received post-doctoral training at the MD Anderson Cancer Center, TX, and University of Miami, FL, USA. She is a recipient of the Young Investigator Award at the ASBMR, USA. She was awarded the Ramanujan Fellowship and Young Scientist Grant from the Department of Science & Technology, India. She is a Research Supervisor in the disciplines of Biochemistry and Nutrition at the Osmania University, Hyderabad, India.
The focus of her research is in two major areas.The Non-Classical functions of Vitamin D. Vitamin D is now known to play an important role in many tissues/organs not involved in calcium homeostasis. Newer functions of this vitamin are being unraveled each year. In recent years, vitamin D deficiency has been reported to be rampant across the world including India. Currently, her group is trying to understand the biochemical and molecular mechanism(s) that play a role during vitamin D deficiency in non-classical target organs such as muscle, heart, brain and adipose tissue.
Another area of her interest is the role of diet in cancer. Dietary ingredients contain phytochemicalsa.k.a ‘nutraceuticals’, which act through multiple molecular targets and help in the prevention or treatment of cancer. Currently, work is in progress to decipher the potential anticancer role of few dietary ingredients using in vitro and in vivo models for breast and prostate cancer. The research work in her lab is funded by DBT, DST and ICMR.